With more than 50,000 members, the National Federation of the Blind is the largest and most influential membership organization of blind people in the United States.  The NFB improves blind people’s lives through advocacy, education, research, technology, and programs encouraging independence and self-confidence.  It is the leading force in the blindness field today and the voice of the nation's blind.  In January 2004 the NFB opened the National Federation of the Blind Jernigan Institute, the first research and training center in the United States for the blind led by the blind.

The ultimate purpose of the National Federation of the Blind is the complete integration of the blind into society on a basis of equality. This objective involves the removal of legal, economic, and social discriminations; the education of the public to new concepts concerning blindness; and the achievement by all blind people of the right to exercise to the fullest their individual talents and capacities. It means the right of the blind to work along with their sighted neighbors in the professions, common callings, skilled trades, and regular occupations.